For most Sjogren’s Syndrome sufferers, one of the first questions after an often long and winding diagnosis is “what can I do about it?” Unfortunately, the question is a bit mixed.
SS has never had a drug approved specifically for treating the disease. Unlike many autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease, SS is not affected by TNF (tumor necrosis factor) inhibitors like Humira and Enbrel. While some newer biologic drugs like Benlysta and Abatacept have shown promise in early trials, they are still years away from approval for treatment of SS. Even anti-malarial drugs such as Plaquenil have not been approved for SS, and the research on their effects is mixed.
On the positive side, there are conventional treatments approved to treat SS symptoms, such as dry eye and dry mouth. There are also a variety of lifestyle changes that SS sufferers have found valuable. Finally, there are experimental therapies available for those who do not want to wait for the long, slow FDA approval process. This includes dedicated information on helminthic therapy.
I have put together a page outlining my own treatment regimen which I have found to reduce my symptoms.